One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Highly challenging to sequence and long overlooked, the human Y chromosome's contributions to health and disease remain largely unknown. A new paper that presents, for the first time, the complete ...

Highly challenging to sequence and long overlooked, the human Y chromosome’s contributions to health and disease remain largely unknown. A new paper that presents, for the first time, the complete ...

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

A major breakthrough in human genetics has been achieved with the complete decoding of the human Y chromosome, opening up new avenues for research into digestive diseases. This milestone, along with ...

Assessments of DNA misrepair, and the resulting effects on the structural integrity of the genome, are critical for evaluating the safety of cell and gene therapy applications. Most genome editing ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

New insights into the Y chromosome, including its role in disease, should flow from the complete DNA sequencing data now achieved by two international research teams. Although it is commonly reported ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...