Evaluation of carboplatin toxicities and efficacy using different body weight descriptors in the Calvert formula. An easy-to-handle DPD deficiency test in saliva to identify patients at high-risk for ...

Purpose: The permeability of 13 different gloves to 13 cytotoxic agents under controlled dynamic conditions is described. Methods: Thirteen cytotoxic agents were prepared at the highest concentrations ...

The emergence of antibody-drug conjugates (ADCs) has seen them become a promising class of anticancer therapeutics, exhibiting better precision and reduced off-target toxicity in targeting cancer ...

Grace Liu (left) is a Technical Account Manager at Sino Biological US Inc. (PA, USA). Grace joined Sino Biological in 2022, supporting CRO services and project management in the western and central US ...

What Are Antimetabolites, and How Do They Work? Antimetabolites are called a “cytotoxic” type of drug because they kill cells. They work by mimicking the molecules that a cell needs to grow. Cells are ...

Antineoplastic (chemotherapy) drugs are medications used to treat cancer. They go by several other names such as anticancer or cytotoxic drugs. The National Cancer Institute’s SEER*RX database lists ...

As pharmaceutical companies embrace antibody-drug conjugates (ADCs) as a way to treat cancer, drug services providers are investing in capacity to meet the companies’ manufacturing needs.

Hainan Simcere Pharmaceutical Co. Ltd. has disclosed antibody-drug conjugates comprising a glycoengineered antibody covalently linked to a cytotoxic drug through a linker reported to be useful for the ...

METUCHEN, N.J.--(BUSINESS WIRE)--Tevogen Bio, a clinical stage biotechnology company, announced that the U.S. Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) ...