For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

Scientists have found that twisting structures in DNA long mistaken for knots are actually something else entirely. Inside cells, DNA gets twisted, copied, and pulled apart. The twists can influence ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

A powerful form of DNA-editing machinery discovered in bacteria might allow us to make much bigger changes to genomes than is currently possible with CRISPR-based techniques. However, it isn’t yet ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...