It’s one of life’s most defining moments—that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for ...

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these ...

Gastrulation is a process common to nearly all metazoan organisms during which an embryo with distinct tissue layers develops out of a seemingly unstructured assembly of cells referred to as 'blastula ...

Jay Shendure is in the Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA, and at the Brotman Baty Institute for Precision Medicine, the Allen Discovery Center for ...

Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as gastrulation, ...

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these ...

A recent study in Advanced Science presents a method for studying early human embryology by bioprinting epiblast-like structures from human-induced pluripotent stem cells (hiPSCs). The model forms a ...

During early development, tissues and organs begin to bloom through the shifting, splitting, and growing of many thousands of cells. A team of MIT engineers has now developed a way to predict, minute ...

Barriers between stem cells play a crucial role in human development—and offer a new potential route for fertility treatment SAN FRANCISCO, CA—As a human embryo grows, a set of molecules directs cells ...

Gastrulation lays the groundwork for the whole human body's development. Researchers have discovered a way to replicate a simplified version of this fundamental process in a dish by beginning with a ...