The majority of drug interactions today are attributed to the cytochrome P450 (CYP450) isoenzyme system. However, new data suggest that transport proteins also play a key role. One such transporter is ...

EM images reveal how Marburg virus slips into human cells, exposing glycoprotein “cap” tricks and weak spots that could guide ...

Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), uses its spike (S) glycoprotein to enter host cells. The S glycoprotein consists of ...

Stanniocalcin-1 (STC1) is a glycoprotein hormone involved in calcium/phosphate homeostasis, which regulates various cellular processes in normal development and tumorigenesis. After analyzing more ...

3D structural findings are reported on a critical component of the Nipah virus' infection mechanism, and how antibodies home in on an important part of the machinery that attaches the virus to host ...

Glycosylation is a critical quality attribute (CQA) for therapeutic proteins, influencing their stability, bioactivity, and immunogenicity. Glycoprotein characterization and glycosylation profiling ...

A team of US-based scientists has recently demonstrated the cryo-electron microscopic structure and antigenicity of the attachment glycoprotein of the Nipah virus. The study is published in the ...

Astellas has become the latest big pharma company to sink some money into immuno-oncology start-up GO Therapeutics, forging an alliance to develop antibodies targeting two glycoprotein targets. The ...

Replacing a step in sample preparation with an automated approach improves both method precision and productivity. Glycosylation is a critical quality attribute (CQA) for therapeutic proteins, ...