The Major Histocompatibility Complex is a genetic region characterized by a high density of genes, many of them involved in the immune response. Of considerable importance are the HLA class I and ...

The major histocompatibility complex (MHC) represents a critical gene family in vertebrates that shapes immune recognition and disease resistance through its extraordinary allelic diversity.

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity.

The study, according to the researchers, is the first to demonstrate the potential use of major histocompatibility complex class II (MHC-II) expression as a predictor of immunotherapy response in ...

This is a preview. Log in through your library . Abstract In many species, individuals prefer mates that are genetically dissimilar at the major histocompatibility complex (MHC), likely because it ...

Which came first, MHC class I or MHC class II? For decades, it has been debated which of these two similar classes came first in evolution. Now, Keiichiro Hashimoto and his group at Fujita Health ...

Lymphomas represent a heterogeneous group of mature immune cell malignancies. Lymphomas are classified on the basis of clinical, molecular, and histological features that include descriptions of ...

Westlake Therapeutics (Hangzhou) Co. Ltd. and affiliated organizations have reported the design and preclinical characterization of novel erythrocytes conjugated to major histocompatibility complex ...

Antigens bound by major histocompatibility complex (MHC) molecules interact with T-cell receptors (TCRs) at the heart of the interface for T-cell recognition. But, many other players are involved.

The repertoire of αβ T cell antigen receptors (TCRs) on mature T cells is selected in the thymus where it is rendered both self-tolerant and restricted to the recognition of major histocompatibility ...

In the ever-evolving world of cell therapy, researchers often turn to T cells—a type of white blood cell—to transform the way we treat cancer. This is true for CAR T therapy, a modern cancer ...

Scientists have identified a key mechanism used by the SARS-CoV-2 virus to evade host immune systems. Scientists at Hokkaido University and Texas A&M University have identified a key mechanism used by ...