A recent study highlights the pivotal role of alternative splicing in controlling plant secondary metabolism, which is crucial for producing bioactive compounds with significant medicinal and ...

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...

Human introns have extensively varying lengths. Previously, only U2AF-dependent splicing was known. Researchers from Fujita Health University now show that splicing in a subset of human short introns ...

Genes contain the essential building instructions for life, guiding cells on which amino acids to assemble in what sequence to produce specific proteins. The human genome codes for about 20,000 such ...

Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have improved in recent years, approximately 30% of patients relapse following ...

Collaboration with UMass Chan Medical School confirmed FMR1-217 as well as an RNA-targeted mechanism to restore functional FMRP protein to develop potential treatments for FXS QurAlis’ preliminary ...

In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...

Superior potency demonstrated versus leading TROP2 ADCs across bladder, lung and breast tumor modelsNovel RNA ...

A team has identified an essential internal control mechanism that can promote the maturation of human stem cell-derived heart muscle cells, possibly leading to new therapies for heart disease and ...

Fiber optic technology has reshaped the way data moves around the world. From undersea cables connecting continents to local ...