Oocyte maturation and follicular development are fundamental processes that underpin female fertility. These processes involve the transformation of primordial follicles into a cohort of mature, ...

One characteristic of oocyte development and physiology that has been a mystery for 60 years is the highly present cytoplasmic lattices within the cytoplasm of mammalian oocytes. These were initially ...

Researchers have found that a carefully orchestrated act of X-chromosome 'yoyo' predicts the successful and efficient development of mammalian egg cells. The findings could pave the way for generating ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

(a) Fluorescence images showing the chromatin in FGO stained with DAPI. Scale bar, 20 μm. Yellow triangles indicate DAPI-dense heterochromatin foci and the red triangles denote the nucleoli or NLBs.

The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these ...