Every morning, millions of adults consume voluminous cups of coffee, seeking the jolting effect of caffeine. As these adults consume their coffee, they do so unaware that some of the youngest ...

In fetal life, peripheral chemoreceptor stimulation by hypoxia or hypercapnia produces bradycardia and peripheral vasoconstriction (1, 2). After birth, however, the same stimuli cause hyperventilation ...

When concentrations of SNO delivered to the dorsocaudal brainstem match the magnitude of peak HVR, the time constants of VSTP after hypoxia and SNO are similar (our unpublished results). Thus VSTP, a ...

This is a preview. Log in through your library . Abstract Cardiorespiratory activity is controlled by a network of neurons located within the lower brainstem. The basic rhythm of breathing is ...

Studies in animal models and humans have identified an important role for peripheral chemoreceptors in the pathogenesis of heart failure. Thus, inhibiting their hyperactivity has been proposed as a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 10 (March 6, 2012), pp. 3766-3771 (6 pages) Chemoreceptor arrays are supra molecular transmembrane ...

Researchers from the University of Missouri are studying potential therapies to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and ...

Apnea, the absence of breathing, is the most frequently reported disorder of breathing control in premature infants, and neonatal care units habitually use methylxanthine derivatives such as caffeine ...