In their upcoming G&D paper, Dr. Robert Tjian (UC Berkeley) and colleagues reveal how histone gene expression is differentially regulated during Drosophila development. The researchers demonstrate ...

Locations of the cis-regulatory elements (CREs) and core promoter motifs CCAAT, Y patch, TATA-box, and TSS/Inr within dicot and monocot promoters. Researchers explain how new sequencing methods can ...

I read with interest Eugene Russo's article on regulated gene therapy.1 For the past six years, I have been developing a system to target genes to specific tissues and regulate their expression using ...

Expert Rev Mol Diagn. 2012;12(4):371-382. Most tumor-related gene miRNAs can have normal regulatory function, but are dysregulated in cancer progression. In the latest edition of the miRBase miRNA ...

Humans have it. So does Drosophila. But not yeast. That "it" is a small pause at the start of gene activity—a brief molecular halt that may have helped life evolve from simple cells to complex animals ...