B cell central tolerance is regulated by the mechanisms of receptor editing and apoptosis, which operate in succession over the course of 2 to 3 days. Receptor editing involves ongoing immunoglobulin ...

Immune tolerance refers to unresponsiveness of the immune system toward certain substances or tissues that are normally capable of stimulating an immune response. Self-tolerance is essential for ...

Regulatory T cells protect the body from misdirected or overly excited immune responses. A new study highlights previously unknown characteristics of these cells that could guide the development of ...

Aimee Pugh Bernard is affiliated with Immunize Colorado as a volunteer and unpaid board member. Every day, your immune system performs a delicate balancing act, defending you from thousands of ...