Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...
Oligonucleotides – short, synthetic sequences of DNA or RNA – have evolved from basic lab reagents to powerful enablers of precision medicine. Once confined to PCR primers and hybridization probes, ...
- The next frontier in oligonucleotide synthesis is the direct synthesis of gene-length sequences. - Ansa synthesized a 1005 base long oligonucleotide with industry-leading accuracy. - Ansa will be ...
The production of short DNA and RNA sequences, called oligonucleotides, is today essential in connection with diagnostics (COVID-19 test), DNA sequencing, gene synthesis for synthetic biology and gene ...
SELEX (Systematic Evolution of Ligands by EXponential enrichment) was first described and used in 1990 to isolate a functional oligonucleotide from a random pool of differently-shaped DNA or RNA ...
MicroRNAs are a class of noncoding regulatory RNA molecules that affect gene expression by binding to 3´-untranslated regions of messenger RNAs (mRNAs). Although recently identified as a new class of ...