Researchers outline why organs from older donors are often discarded and identify the biological and immunological pathways that make them vulnerable to injury. They also highlight emerging ...

Their data suggests that tweaking the expression of FDX2 could make up for the loss of frataxin, the protein tied to FA's development.

Maintaining long-term health has become a major challenge, driving research into ways to extend “healthspan” rather than ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial ...

Sickle cell disease is associated with chronic oxidative stress, hemolysis, inflammation, and progressive multi--organ injury, including significant cardiopulmonary complications. Mitochondrial ...

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury.

New research led by Thomas Schwarz, Ph.D., and Chen Ding, Ph.D., of the Schwarz Lab at Boston Children's Hospital, has identified a promising therapeutic target to stop the damage to RGCs.

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular ...