RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

AlidaBio today announced the launch of the EpiPlex™ Duo-Mod™ Service, a turnkey offering that maps and quantifies m6A and ...

Sequencing diverse populations revealed over 41,000 transcripts missing in Eurocentric references, exposing ancestry bias ...

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells—an achievement that could ...

Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...

Once considered passive messengers of genetic information, RNA molecules are now understood to play an active and dynamic role in gene regulation, modulated by a rich layer of chemical modifications ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

CHICAGO – A new gene expression atlas developed using single-cell RNA sequencing data shows how normal hematopoietic cells differentiate and was used to catalog the multiple ways that aberrant ...

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

RNA modifications are increasingly recognized as clinically relevant biomarkers, revealing immune dysregulation in autoimmune disease, early oncogenic signaling, and RNA misprocessing in ...